Related Experiment Video
Updated: Feb 2, 2026

High-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts
Published on: December 20, 2024
Laparoscopic Resection of an Appendix Mucocele in a Breast Cancer Patient
Scarlett Hao1, Roberta Lilly2, Hugo J R Bonatti3
1Vidant Medical Center, Greenville, NC, USA.
Background:
Acute appendicitis may be treated with antibiotics, but most surgeons offer laparoscopic appendectomy (LA). Appendiceal mucocele (AMC) is a rare disorder. Surgical removal is recommended due to the risk of pseudomyxoma peritonei. LA has been suggested for this condition. Although rare, breast cancer (BC) may metastasize to the appendix. An appendiceal mass in a breast cancer patient should be approached as a possible metastatic focus until proven otherwise.
Case Presentation:
A 45-year-old Caucasian woman with invasive lobular BC underwent bilateral mastectomy. An AMC was found on CT scan. LA was done with a strict minimal touch technique. The appendix was resected with a 1 cm margin of the cecal pole, and the specimen was removed from the abdomen in a retrieval bag. Pathology showed benign cystadenoma. The patient had an uneventful postoperative course.
Conclusion:
This case highlights the diagnostic challenge of an appendiceal mass in a BC patient. BC patients with AMC should undergo appendectomy to rule out metastatic disease and to prevent pseudomyxoma peritonei. LA can be performed safely in patients with AMC.
Insights
Laparoscopic appendectomy (LA) is a safe option for appendiceal mucocele (AMC) in breast cancer (BC) patients. This approach helps rule out metastatic disease and prevents pseudomyxoma peritonei.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
Background:
- Appendiceal mucocele (AMC) requires surgical removal due to pseudomyxoma peritonei risk.
- Breast cancer (BC) can rarely metastasize to the appendix, presenting a diagnostic challenge.
- Laparoscopic appendectomy (LA) is a standard treatment for acute appendicitis and has been suggested for AMC.
Observation:
- A 45-year-old woman with invasive lobular BC presented with an appendiceal mass detected via CT scan.
- The patient underwent a bilateral mastectomy followed by LA using a minimal touch technique.
- The appendix was resected with a 1 cm margin and removed in a retrieval bag.
Findings:
- Pathology confirmed a benign cystadenoma of the appendix.
- The patient experienced an uncomplicated postoperative recovery.
- This case underscores the diagnostic complexity of appendiceal masses in BC patients.
Implications:
- Appendectomy in BC patients with AMC is crucial for excluding metastatic disease and preventing complications.
- LA is a safe and effective surgical option for managing AMC in breast cancer patients.
- Early diagnosis and surgical intervention are vital for optimal patient outcomes.
Related Concept Videos
Cancer
Patient-centered Care
What is Cancer?
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Drug Dosing: Geriatric Patients
Drug Dosing: Obese Patients
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

