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Association between handgrip strength and vascular function in patients with hypertension
Dalton de Lima-Junior1, Breno Quintella Farah2, Antonio Henrique Germano-Soares3
1a Department of Physical Education, Federal University of Pernambuco , Recife , PE , Brazil.
Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|November 10, 2018
Summary
Higher handgrip strength in hypertensive patients is linked to lower arterial stiffness, specifically the ambulatory arterial stiffness index (AASI) and augmentation index at 75 heartbeats (AIx@75). This suggests muscle strength may play a role in vascular health for those with hypertension.
Area of Science:
- Cardiovascular Medicine
- Physiology
- Hypertension Research
Background:
- Increased handgrip strength correlates with reduced mortality in general populations.
- Arterial stiffness is a known predictor of cardiovascular mortality in hypertensive individuals.
- The relationship between muscle strength and arterial stiffness in hypertension remains understudied.
Purpose of the Study:
- To investigate the association between handgrip strength and arterial stiffness parameters in patients with hypertension.
- To determine if muscle strength is a predictor of vascular stiffness in this specific patient group.
Main Methods:
- Seventy-two hypertensive patients underwent assessments.
- Arterial stiffness was measured using ambulatory arterial stiffness index (AASI), carotid-femoral pulse wave velocity (cfPWV), and augmentation index (AIx, AIx@75).
- Handgrip strength was measured using a digital dynamometer; regression models were applied.
Main Results:
- A negative association was observed between handgrip strength and AASI and AIx@75, even after adjusting for confounding factors.
- Handgrip strength was not significantly associated with cfPWV or AIx.
- The association with AASI and AIx@75 remained significant after adjustments.
Conclusions:
- Handgrip strength demonstrates a negative association with AASI and AIx@75 in hypertensive patients.
- Muscle strength may be a relevant factor in arterial stiffness for individuals with hypertension.
- Further research is warranted to explore the clinical implications of this finding.
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