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Protein nanoparticles with ligand-binding and enzymatic activities

Olga V Morozova1,2, Elizaveta R Pavlova1,3, Dmitry V Bagrov1,4

  • 1Department of Biophysics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency (FRCC PCM), Moscow, Russia, omorozova2010@gmail.com.

International Journal of Nanomedicine
|November 15, 2018
PubMed
Summary

A new method creates stable protein nanoparticles (NPs) from various proteins using nanoprecipitation. These NPs maintain biological activity, including ligand binding and enzymatic functions, without cross-linking.

Keywords:
ELISAatomic force and electron microscopyenergy-dispersive X-ray spectroscopylysozyme activity assaynanoprecipitationprotein nanostructuresultraviolet and circular dichroism spectroscopy

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