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Updated: Feb 2, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
Novel Pharmacotherapy for Hypertrophic Cardiomyopathy
Timothy C Wong1, Matthew Martinez2
1Department of Medicine, Division of Cardiology, University of Pittsburgh School of Medicine, UPMC Hypertrophic Cardiomyopathy Center, UPMC Heart and Vascular Institute, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Abstract:
Medical therapy for hypertrophic cardiomyopathy (HCM) has focused on minimizing the impact of symptoms due to left ventricular outflow tract obstruction and diastolic dysfunction. This article briefly discusses currently available therapy and focuses on both clinically available medications with novel applications for HCM as well as novel medications under development with specific indication for HCM. Finally, a brief summary of the current gaps and potential targets for pharmacotherapy is discussed.
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