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Updated: Feb 2, 2026
06:10
An Ex Vivo Choroid Sprouting Assay of Ocular Microvascular Angiogenesis
Published on: August 6, 2020
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Qualitative comparison of choroidal vascularity measurement algorithms
Mohammed A Rasheed1, Niroj K Sahoo1, Abhilash Goud1
1Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Indian Journal of Ophthalmology
|November 20, 2018
Summary
Automated binarization of choroidal vasculature is more accurate and faster than manual methods. This technique improves the analysis of optical coherence tomography (OCT) scans for better diagnostic insights.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Accurate analysis of choroidal vasculature is crucial for diagnosing and monitoring various eye diseases.
- Manual binarization techniques for optical coherence tomography (OCT) scans can be time-consuming and prone to interobserver variability.
Purpose of the Study:
- To compare the accuracy and reliability of automated versus manual binarization techniques for choroidal vasculature analysis using swept source OCT (SS-OCT).
Main Methods:
- A retrospective study analyzed 98 eyes from 60 healthy subjects using fovea-centered SS-OCT scans.
- Choroidal area was binarized using both manual and automated methods.
- Two masked graders subjectively graded choroidal vessel visualization, with intergrader and intragrader variability assessed.
Main Results:
- Automated binarization achieved significantly higher accuracy (93.38% ± 1.70%) compared to manual binarization (78.06% ± 2.92%) (P < 0.001).
- Manual binarization exhibited significant variability and poor agreement among observers.
Conclusions:
- Automated image binarization is a faster and more accurate method for analyzing choroidal vasculature from SS-OCT images.
- This technique offers improved reliability over manual methods for clinical applications.
Keywords:
Automated binarizationbinarizationchoroidal segmentationchoroidal vascularity indexmanual binarizationMore Related Videos
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