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Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
Published on: August 11, 2017
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Bioprinting in Vascularization Strategies
Mahboubeh Jafarkhani1, Zeinab Salehi1, Amir Aidun2,3
1School of Chemical Engineering, College of Engineering, University of Tehran, Iran.
Iranian Biomedical Journal
|November 22, 2018
Summary
Three-dimensional (3D) printing enables precise cell placement for tissue engineering. This technology shows promise for creating vascular networks to improve engineered tissue viability.
Area of Science:
- Biotechnology
- Regenerative Medicine
- Biomaterials Engineering
Background:
- Tissue engineering faces challenges in creating functional vascular networks essential for cell survival.
- Three-dimensional (3D) printing offers a novel approach to address this limitation by fabricating vascularized constructs.
Purpose of the Study:
- To explore the application of 3D printing in vascular tissue engineering.
- To highlight the potential of 3D printing in mimicking in vivo vascular conditions.
Main Methods:
- Utilizing various 3D printing techniques, such as selective laser sintering and extrusion, to position vascular cells and biomaterials.
- Developing cell-laden constructs with precise spatial arrangements.
Main Results:
- 3D printing allows for accurate positioning of cells and biomaterials, crucial for engineered tissue development.
- The technology facilitates the creation of vascular structures within engineered tissues, potentially enhancing cell viability.
Conclusions:
- 3D printing is a key technology in vascular tissue engineering, offering automation and high cell density capabilities.
- Further improvements in resolution, printing speed, and material options will expand the application of 3D printing in this field.
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