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Updated: Feb 2, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
Idea to explore: The structure of the oxygen and iron ion
1Institute of Biochemistry, Medical Faculty, Ljubljana, Slovenia.
Abstract:
Understanding diamagnetism of oxygenated and paramagnetism of deoxygenated hemoglobin, an important topic in (bio) chemistry for medical students, begins with the understanding of the detailed structure of the oxygen molecule. It continues with a short description of the structures of reactive oxygen species: the singlet form of oxygen, the superoxide, and peroxide anions. The article then describes the high spin and low spin form of the iron ion with its d-orbitals and explains why both forms with different diameters exist in the heme part. At the end, medical applications of the acquired knowledge are presented: the cooperative effect in hemoglobin and the principles of magnetic resonance imagining. © 2018 International Union of Biochemistry and Molecular Biology, 46(6):630-633, 2018.
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