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Pediatric Abdominal Organ Transplantation
Christine S Hwang1, Malcolm Macconmara1, Dev M Desai1
1Surgery, Solid Organ Transplant Program, Children's Medical Center, University of Texas Southwestern Medical Center, MC B2.02, 1935 Medical District Drive, Dallas, TX 75235, USA.
The Surgical Clinics of North America
|November 26, 2018
Summary
Pediatric liver and kidney transplants are now standard treatments for children with end-stage organ failure. Advances have expanded indications, donor types, and recipient ages, establishing these procedures as essential care.
Area of Science:
- Pediatric Surgery
- Transplantation Medicine
- Nephrology and Hepatology
Background:
- Pediatric liver and kidney transplantation are established treatments for end-stage organ disease in children.
- Historical milestones include the first kidney transplant (1954) and liver transplant (1963).
Purpose of the Study:
- To review the evolution and current status of pediatric liver and kidney transplantation.
- To highlight advancements in indications, donor sources, and recipient age ranges.
Main Methods:
- Literature review of historical and contemporary pediatric transplantation practices.
- Analysis of the expanding scope of visceral organ transplantation in pediatric patients.
Main Results:
- Indications for pediatric organ transplantation have broadened significantly.
- Technological and surgical advancements have enabled transplantation across wider recipient and donor age groups.
- Innovations include simultaneous multivisceral transplants, living-donor organs, and donation-after-cardiac-death organs.
Conclusions:
- Pediatric liver and kidney transplantation are now the standard of care for pediatric end-stage renal and liver failure.
- These complex procedures have evolved to meet the needs of a diverse pediatric population.
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