Influence of surface topography on bacterial adhesion: A review (Review)

Bacterial adhesion and biofilm formation are ubiquitous undesirable phenomena in the marine industry and the medical industry, usually causing economic losses and serious health problems. Numerous efforts have been made to reduce bacterial adhesion and subsequent biofilm formation, most of which are based on the release of toxic biocides from coatings or substrates. In recent years, surface topography has been found to substantially influence the interaction between bacteria and surfaces. This review summarizes previous work dedicated in searching for the relationship between bacterial adhesion and surface topography in the last eight years, as well as the proposed mechanisms by which surface topographic features interact with bacterial cells. Next, various natural and artificial surfaces with bactericidal surface topography along with their bactericidal mechanisms and efficiency are introduced. Finally, the technologies for constructing antibacterial surfaces are briefly summarized.