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Functionalized phosphorescent nanoparticles in (bio)chemical sensing and imaging - A review
Pablo Llano Suárez1, Marta García-Cortés1, María Teresa Fernández-Argüelles2
1Department of Physical and Analytical Chemistry, University of Oviedo, Avda. Julián Clavería 8, Oviedo 33006, Spain.
Analytica Chimica Acta
|November 29, 2018
Summary
Phosphorescent nanoparticles offer advanced optical sensing capabilities, outperforming molecular fluorophores in environmental, industrial, and biomedical applications. This review details their design, features, and applications in chemical sensing and bioimaging.
Area of Science:
- Materials Science
- Nanotechnology
- Analytical Chemistry
Background:
- Inorganic nanoparticles are versatile materials with significant potential in optical (bio)sensing.
- Fluorescent nanoparticles are widely used for sensing and imaging, offering advantages over molecular fluorophores.
- Hybrid phosphorescent nanoparticles combine nanomaterial properties with phosphorescence emission for enhanced sensing.
Purpose of the Study:
- To review progress in phosphorescent nanoparticle-based sensors.
- To update the database of sensors based on various sensing targets.
- To highlight applications in environmental, industrial, and biomedical fields.
Main Methods:
- Discussion of the synergy between nanomaterials and phosphorescence detection.
- Assessment of nanomaterial types and features used in phosphorescence sensing.
- Presentation of specific examples in chemical sensing and bioimaging.
Main Results:
- Phosphorescent nanoparticles demonstrate significant potential in optical sensing.
- Hybrid phosphorescent nanoparticles offer unique size- and shape-dependent properties.
- Applications span environmental, industrial, and biomedical sensing and imaging.
Conclusions:
- Phosphorescent nanoparticles represent a promising platform for advanced analytical devices.
- Continued research in nanomaterial design will drive future innovations in sensing technology.
- These nanomaterials offer a powerful alternative to traditional molecular luminophores.
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