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Updated: Aug 5, 2026

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Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
Published on: February 20, 2017
[Changes in the volutin levels in yeast cells during cell cycle]
Biofizika
|May 1, 1988
Summary
Volutin, an inorganic polyphosphate granule in yeast, may regulate cell division initiation in Saccharomyces cerevisiae. However, cell division does not appear to influence volutin accumulation.
Area of Science:
- Microbiology
- Cell Biology
- Biochemistry
Background:
- Saccharomyces cerevisiae is a model organism for studying eukaryotic cell division.
- Volutin granules (inorganic polyphosphates) are found in yeast vacuoles.
- The role of volutin in cell cycle regulation is not fully understood.
Purpose of the Study:
- To investigate the relationship between cell number distribution, volutin content, and cell volume in Saccharomyces cerevisiae.
- To analyze the dynamics of yeast population age composition during growth medium shifts.
- To determine if volutin acts as a regulator in the yeast cell division cycle.
Main Methods:
- Analysis of dimeric cell number distribution based on cell volume and volutin content.
- Monitoring population age composition dynamics over time.
- Observing changes in growth medium from limiting to balanced conditions.
Main Results:
- Cell number distribution in Saccharomyces cerevisiae correlates with cell volume and volutin content.
- Volutin accumulation was observed to potentially regulate the initiation of the cell division cycle.
- No adverse effect of cell division initiation on volutin accumulation was detected.
Conclusions:
- Volutin may play a regulatory role in triggering cell division in Saccharomyces cerevisiae.
- Yeast cell division initiation does not negatively impact volutin accumulation.
- Further research is warranted to elucidate the precise mechanisms of volutin-mediated cell cycle regulation.
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