[Secondary osteoporosis. Glucocorticoid excess-related osteoporosis.]

Glucocorticoid(GC)excess is one of the most common causes of secondary osteoporosis, which can be associated with a disease(GC excess due to Cushing's syndrome)or with a treatment(GC medications). In addition to Cushing's syndrome, subclinical Cushing's syndrome, which occurs more frequently, can also increase the risk of fractures. Thus, it is important to consider these diseases when making the diagnosis for osteoporosis. GC-induced osteoporosis leads to reduction of bone mineral density and increased risk of fracture from the early stage after initiation of GC treatment, and thus requires management from the time of initiation. The 2014 revised Guidelines on the Management and Treatment of GC-induced Osteoporosis should be used routinely in the clinical settings as they introduce a scoring system that is easily adoptable.