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Updated: Feb 1, 2026

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry
Published on: November 25, 2011
Cutaneous Melanoma-A Review in Detection, Staging, and Management
Rebecca I Hartman1, Jennifer Y Lin1
1Department of Dermatology, Brigham and Women's Hospital, 41 Avenue Louis Pasteur, Room 319, Boston, MA 02115, USA; Melanoma Program, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA.
Abstract:
Melanoma is an increasingly common cancer in the United States, although mortality has likely stabilized. Diagnosis relies on a skilled practitioner with the aid of dermoscopy and initial local surgical management is a mainstay of treatment. Recent changes in staging emphasize continued use of sentinel lymph node biopsy to aid in prognostication although routine complete lymph node dissection has fallen out of favor. Advances in systemic treatment options, including targeted and immunotherapy, have dramatically changed the treatment paradigm for advanced melanoma and improved outcome. Prevention via sun protection remains a critical tool in efforts to limit the burden of this disease.
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