Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreasing Function01:27

Decreasing Function

290
A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
290
Decreased Body Temperature01:29

Decreased Body Temperature

1.1K
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
1.1K
Decreased pulse rate01:14

Decreased pulse rate

900
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
900
Clinical Trials: Overview01:11

Clinical Trials: Overview

4.9K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.9K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

411
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
411
Clinical Trials01:16

Clinical Trials

10.5K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pressure points: A pilot study using the NASA-TLX tool to measure the intensity of Acute care surgery work.

American journal of surgery·2026
Same author

Determining Optimal Fractionation of Neoadjuvant Radiation in Low-Risk, Early-Stage Breast Cancer-Randomized SIGNAL Clinical Trial.

Cancers·2026
Same author

Universal healthcare: more tax, less litigation?

American journal of surgery·2026
Same author

Reconciling the academic mission with workforce reality in acute care surgery.

The journal of trauma and acute care surgery·2026
Same author

A Consensus Approach to the Incorporation of Total Neoadjuvant Therapy in a Treatment Algorithm for Stage I-III Resectable Rectal Cancer.

Current oncology (Toronto, Ont.)·2026
Same author

A qualitative exploration of patient perspectives regarding patient education during their colorectal surgical experience.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2026
Same journal

Real-world Safety and Performance of the Symani Surgical System® in Microsurgical Reconstructive Procedures: Primary Results from the PRIMO Study.

Annals of surgery·2026
Same journal

Revisiting Simultaneous Liver and Kidney Transplantation from Donors After Circulatory Death in the Era of Machine Perfusion Technologies: A US Nationwide Analysis of 10,687 Cases.

Annals of surgery·2026
Same journal

The International Medical Graduate Paradox.

Annals of surgery·2026
Same journal

Defining the Incremental Value of Endoscopic Ultrasound in Assessing Pancreatic Cystic Neoplasms.

Annals of surgery·2026
Same journal

Trends in Metabolic and Bariatric Surgery and GLP-1 Receptor Agonist Use Among Adolescents with Severe Obesity.

Annals of surgery·2026
Same journal

The Ambulatory Surgery Center Paradox: Why 60% of Surgeries Occur Where 2% of AI Research Happens.

Annals of surgery·2026
See all related articles

Related Experiment Video

Updated: Feb 1, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

882

Negative Pressure Wound Therapy Use to Decrease Surgical Nosocomial Events in Colorectal Resections (NEPTUNE): A

Patrick B Murphy1, Sarah Knowles, Sami A Chadi

  • 1Division of General Surgery, Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Annals of Surgery
|December 1, 2018
PubMed
Summary
This summary is machine-generated.

Negative pressure wound therapy (NPWT) did not reduce surgical site infections (SSIs) in closed incisions after colorectal surgery compared to standard dressings. This study found no significant difference in SSI rates or hospital stay between the two treatment groups.

More Related Videos

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

2.9K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.5K

Related Experiment Videos

Last Updated: Feb 1, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

882
Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

2.9K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.5K

Area of Science:

  • Colorectal surgery
  • Wound healing
  • Infection control

Background:

  • Surgical site infections (SSIs) are a significant cause of morbidity following colorectal surgery.
  • The prophylactic efficacy of negative pressure wound therapy (NPWT) for SSIs in closed incisions remains unestablished.
  • This study investigated the potential benefit of NPWT in reducing SSIs after colorectal procedures.

Purpose of the Study:

  • To determine if negative pressure wound therapy (NPWT) reduces surgical site infection (SSI) rates in primarily closed incisions.
  • To compare the incidence of SSIs in patients receiving NPWT versus standard postoperative dressings after open colorectal surgery.

Main Methods:

  • A randomized controlled trial involving 300 patients undergoing elective open colorectal surgery.
  • Patients were assigned to receive either prophylactic NPWT or standard gauze dressing.
  • The primary endpoint was the 30-day SSI rate, assessed by blinded wound care experts.

Main Results:

  • No significant difference in the 30-day SSI incidence was observed between the NPWT group (32%) and the standard dressing group (34%) (P = 0.68).
  • Median length of hospital stay was identical for both groups at 7 days.
  • Subgroup analysis of patients with a stoma also showed no difference in SSI rates between the groups (38% vs 33%, P = 0.66).

Conclusions:

  • Prophylactic application of NPWT to primarily closed incisions following open colorectal surgery did not decrease the rate of SSIs compared to standard gauze dressings.
  • NPWT is not associated with a reduction in SSIs in this patient population.
  • Further research may be needed to explore NPWT in different surgical contexts or patient groups.