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Neurocognitive function in moderate-severe pediatric atopic dermatitis: A case-control study
Lacey L Kruse1,2, Ahuva Cices2, Anna B Fishbein3
1Division of Dermatology, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois.
Pediatric Dermatology
|December 4, 2018
Summary
Children with atopic dermatitis (AD) did not show a higher prevalence of attention deficit hyperactivity disorder (ADHD). However, they did exhibit increased inattention and other ADHD-associated behaviors.
Area of Science:
- Pediatric Dermatology
- Neurodevelopmental Disorders
- Child Psychology
Background:
- Previous studies suggest a link between atopic dermatitis (AD) and attention deficit hyperactivity disorder (ADHD).
- AD symptoms like poor sleep and itching may contribute to ADHD-like behaviors.
Purpose of the Study:
- To investigate the prevalence of ADHD in children with moderate-to-severe AD.
- To compare ADHD symptoms and behaviors in children with AD versus healthy controls.
Main Methods:
- A case-control study involving children aged 6-17 years with moderate/severe AD and age/sex-matched healthy controls.
- Screening for ADHD using parent-completed Vanderbilt assessments.
Main Results:
- No significant difference in ADHD screening rates between children with AD (11.7%) and controls (5.56%).
- Children with AD were more likely to display inattention and other ADHD-associated behaviors compared to controls.
Conclusions:
- The study cohort with moderate-to-severe AD did not show a significantly increased prevalence of ADHD.
- Children with moderate-to-severe AD exhibited increased neurocognitive symptoms, particularly inattention.
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