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Updated: Feb 1, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Copper(I)-Catalyzed Enantioselective 1,6-Borylation of α,β,γ,δ-Unsaturated Phosphonates
1Department of Chemistry and Institute of Basic Science , Sungkyunkwan University , Suwon 16419 , Korea.
Abstract:
Copper(I)-catalyzed asymmetric 1,6-borylation of 1,3-dienylphosphonates was achieved using ( S, S)-Ph-BPE as a chiral ligand. Regio-, stereo-, and enantioselective borylation successfully proceeded to afford phosphonate-containing allylboronates, with high enantioselectivity up to 97% ee. Further applications of the resulting products generated a valuable phosphonate analogue of γ-butyrolactone.
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