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Copper-Catalyzed Asymmetric Hydroboration of Cyclic Dienes

Jieun You¹, Jung Tae Han², Jaesook Yun¹

¹Department of Chemistry, Sungkyunkwan University, Suwon, South Korea.

Chemistry, an Asian Journal

|January 14, 2026

Abstract

None:

A copper-catalyzed enantioselective hydroboration of cyclic dienes, which afford enantioenriched allylboronates, is disclosed. This reaction is catalyzed by a chiral bisphosphine-Cu complex in combination with commercially available pinacolborane as the hydroborane source. The method is applicable to 1-aryl-cyclohexadienes and 1,2-dihydropyridine derivatives, affording allylboronate products in high regio- and enantioselectivity. The obtained allylboronates serve as versatile intermediates for the synthesis of diverse chiral compounds.

Keywords:

copper cyclic dienes enantioselectivity hydroboration regioselectivity

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