Related Experiment Video
Updated: Feb 1, 2026
07:30
Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
4.4K
Marginal kidney transplantation: the road less traveled
Neeraj Sharma1, Arnav Mahajan, Yasir A Qazi
1University of Southern California - Keck School of Medicine, Los Angeles, California, USA.
Current Opinion in Organ Transplantation
|December 4, 2018
Summary
Utilizing marginal kidneys for transplantation offers a survival benefit over dialysis or waiting. This approach can reduce kidney discard rates and improve patient outcomes, making it a cost-effective strategy.
Area of Science:
- Nephrology
- Transplantation Medicine
- Public Health
Background:
- Kidney transplantation significantly improves survival and quality of life compared to dialysis.
- A growing demand for kidney transplants leads to prolonged waiting times for many patients.
- Reducing the kidney discard rate is crucial to address the organ shortage.
Purpose of the Study:
- To review recent literature on marginal kidney transplantation.
- To evaluate the effectiveness and cost-effectiveness of using marginal kidneys in transplantation.
- To provide evidence supporting the use of marginal kidneys to alleviate organ shortages.
Main Methods:
- Review of recent scientific literature on marginal kidney transplantation.
- Analysis of data regarding kidney discard rates, particularly for high-KDPI kidneys.
- Evaluation of survival benefits and cost-effectiveness of marginal kidney transplants.
Main Results:
- Over 60% of high Kidney Donor Profile Index (KDPI) kidneys are discarded.
- Transplantation of high-KDPI kidneys demonstrates a survival advantage despite increased post-transplant costs, proving cost-effective.
- Marginal kidney transplantation offers a survival benefit compared to remaining on the waitlist.
Conclusions:
- Marginal kidney transplantation provides a survival benefit over dialysis or waiting for a low-KDPI kidney.
- Clinicians should strongly consider marginal kidney transplantation instead of waiting for an ideal organ offer.
- Increased utilization of marginal kidneys can minimize kidney discard rates and improve patient survival.
Related Concept Videos
01:28Kidney Transplant I: Introduction
451
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
451
01:04Travelling Waves
7.1K
A wave is a disturbance that propagates from its source, repeating itself periodically, and is typically associated with simple harmonic motion. Mechanical waves are governed by Newton's laws and require a medium to travel. A medium is a substance in which a mechanical wave propagates, and the medium produces an elastic restoring force when it is deformed.
Water waves, sound waves, and seismic waves are some examples of mechanical waves. For water waves, the wave propagation medium is...
Water waves, sound waves, and seismic waves are some examples of mechanical waves. For water waves, the wave propagation medium is...
7.1K
01:26Kidney Transplant II: Surgical Procedure
412
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
412
01:16Kidney Transplant III: Nursing Management
399
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
399
01:27Traveling Waves: Lossless Lines
480
The provided content explores the behavior of traveling waves on single-phase lossless transmission lines. It begins with a single-phase two-wire lossless transmission line of length Δx, characterized by a loop inductance LH/m and a line-to-line capacitance C F/m. These parameters result in a series inductance LΔx and a shunt capacitance CΔx.
480
01:17Design Example: Alignment of a Road Line Using GIS
350
The alignment of a road line using Geographic Information Systems (GIS) is a critical process in civil engineering, combining advanced technology with practical decision-making. This methodology begins with the collection of geospatial data, including information on land cover, geomorphology, drainage patterns, slope, and contour details. Such data is typically acquired through satellite imagery and GIS tools, offering a comprehensive understanding of the terrain.Once the data is gathered, it...
350