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Updated: Feb 1, 2026

A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice
Published on: November 24, 2020
[CLINICAL FEATURES OF ENDOMETRIOSIS IN WOMEN IN PERIMENOPAUSE]
N Zakharenko1, N Kovalenko1, I Manoliak1
1Institute of Pediatrics, Obstetrics and Gynecology named E.M. Lukyanova of the NAS of Ukraine, Department of Endocrine Gynecology; State Clinical Hospital N9, Department of Gynecology, Kiev, Ukraine.
Abstract:
The aim of the research is the assessment of the features of the course of endometriosis in women in perimenopause. The exanimated group of patients consisted of 106 women with endometriosis and climacteric syndrome and 64 women with endometriosis without climacteric syndrome. The comparison group consisted of 70 women without endometriosis and symptoms of climacteric syndrome. The age of the examined women was from 39 to 55 years. We analyzed the leading complaints, the menstrual function and the severity of the pain manifestations in the examined patients. The results of the studies have shown that the main manifestations of endometriosis, such as hyperpolimenorrhea and pain syndrome, tend to fade with the onset of climacteric syndrome. The psycho-emotional disorders are on the first place in patients with endometriosis in perimenopause.
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