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Updated: Feb 1, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Afamelanotide in the Treatment of Dermatologic Disease
Morgan M McNeil1, Amanda F Nahhas2,3, Taylor L Braunberger2
1Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA
Abstract:
Afamelanotide, an α-melanocyte stimulating hormone analogue, has become an emerging therapeutic option for a variety of skin conditions previously refractory to other treatments. Its efficacy has been demonstrated in several dermatologic conditions, including erythropoietic protoporphyria (EPP), solar urticaria, polymorphic light eruption (PMLE), vitiligo, acne, and Hailey-Hailey disease. Its relatively low risk side effect profile makes it an attractive treatment option and also paves the way for innovative use in other disorders.
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