Related Experiment Video
Updated: Feb 1, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
Draft Opioid-Prescribing Guidelines for Uncomplicated Normal Spontaneous Vaginal Birth
J Rebecca Mills1, Mary Margaret Huizinga, Scott B Robinson
1University of Illinois at Chicago, Chicago, Illinois; Novartis Oncology, East Hanover, New Jersey; U.S. Department of Health and Human Services, Washington, DC; and Premier, Inc, Charlotte, North Carolina.
Opioid prescribing during uncomplicated vaginal delivery is common, with over 78% of women receiving them during hospitalization. A Delphi survey of experts led to seven consensus guidelines for improved pain management in this population.
Area of Science:
- Obstetrics and Gynecology
- Pain Management
- Public Health
Background:
- Acute pain is common during and after uncomplicated vaginal delivery.
- Current clinical practice guidelines for opioid prescribing in this specific obstetric population are lacking.
- The Centers for Disease Control and Prevention (CDC) recommends improved opioid-prescribing practices.
Purpose of the Study:
- To determine the prevalence of opioid administration for uncomplicated vaginal delivery.
- To develop consensus-based guidelines for pain management in this patient group.
Main Methods:
- Analysis of a national healthcare database (2014-2016) for opioid use in 49,133 women.
- Electronic Delphi survey with 14 obstetric expert participants.
- Adaptation of CDC opioid guidelines for the inpatient obstetric population.
Main Results:
- 78.2% of women received opioids during hospitalization; 29.8% received them at discharge.
- Descriptive statistics characterized patient and hospital factors associated with opioid administration.
- Seven of eight adapted guidelines were endorsed by expert panelists after three survey rounds.
Conclusions:
- Significant opioid administration occurs during and at discharge for uncomplicated vaginal births.
- Draft consensus guidelines were developed to address the lack of specific clinical practice guidelines.
- These guidelines provide a foundation for future research and broader clinical adoption.
More Related Videos
09:05Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
Published on: August 30, 2021
09:01Performing Vaginal Lavage, Crystal Violet Staining, and Vaginal Cytological Evaluation for Mouse Estrous Cycle Staging Identification
Published on: September 15, 2012
Related Concept Videos
Spontaneity
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Birth Control Methods
Opioid Receptors: Overview
Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Guidelines for Nursing Documentation I
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.