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Bartonella endocarditis

Roxana Ghashghaei1, Irene Thung1, Grace Y Lin1

  • 1University of California San Diego Medical Center, San Diego, CA, USA.

Journal of Cardiology Cases
|December 15, 2018
PubMed

Insights

Blood culture-negative endocarditis is difficult to diagnose. This case highlights *Bartonella henselae* as a cause of culture-negative endocarditis, emphasizing diagnostic and treatment challenges.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Blood culture-negative endocarditis (BCNE) poses significant diagnostic challenges.
  • Bacterial endocarditis often requires identification of causative agents through blood cultures, which can be negative in certain infections.

Purpose of the Study:

  • To report a case of delayed diagnosis of *Bartonella henselae* endocarditis.
  • To underscore the role of *Bartonella* species in BCNE.
  • To illustrate diagnostic and therapeutic hurdles associated with *Bartonella* endocarditis.

Main Methods:

  • Case report detailing a patient with endocarditis.
  • Review of diagnostic procedures and treatment course.
  • Literature review on *Bartonella* endocarditis.

Main Results:

  • A diagnosis of *Bartonella henselae* endocarditis was significantly delayed.
  • The case underscores the need for considering atypical pathogens in BCNE.
  • Successful treatment was achieved after appropriate diagnosis.

Conclusions:

  • *Bartonella* species are an important, often overlooked, cause of culture-negative endocarditis.
  • Early consideration of *Bartonella* in unexplained endocarditis is crucial for timely diagnosis and effective management.
  • Diagnostic strategies for BCNE should include serological and molecular methods for *Bartonella*.

Keywords:
Aortic valve vegetationBartonella endocarditisCulture negative endocarditis

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