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Related Concept Videos

Adhesion01:14

Adhesion

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Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
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Immunoglobulin-like Cell Adhesion Molecules01:31

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
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Intracellular Signaling Affects Focal Adhesions01:17

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Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
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Cell Adhesion Molecules - Types and Functions01:20

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Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
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Laminins are heterotrimeric proteins with high molecular mass found in the extracellular matrix. Each laminin molecule is composed of three chains, viz. alpha, beta, and gamma, coded by five, four, and three paralogous genes, respectively. Laminins are categories based on the compositions of the three chains.
In humans, the five forms of alpha chains are LAMA 1, LAMA 2, LAMA 3, LAMA 4, and LAMA 5. The four forms of beta chains are LAMB 1, LAMB 2, LAMB 3, and LAMB 4. The three forms of gamma...
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Imaging Molecular Adhesion in Cell Rolling by Adhesion Footprint Assay
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Photodetachable Adhesion.

Yang Gao1,2, Kangling Wu1,2, Zhigang Suo3

  • 1State Key Laboratory of Strength and Vibration of Mechanical Structures, Xi'an, Shaanxi, 710049, China.

Advanced Materials (Deerfield Beach, Fla.)
|December 15, 2018
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel photodetachable adhesion method. This technique allows for strong bonding that can be easily and quickly released using specific light frequencies, minimizing discomfort and damage.

Keywords:
hydrogelslight-triggeredphotodetachable adhesiontopological adhesion

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Adhesion Science

Background:

  • Strong adhesion often leads to difficult and painful detachment.
  • Current adhesion methods lack on-demand, non-destructive release mechanisms.

Purpose of the Study:

  • To develop a novel adhesion system that provides strong bonding yet allows for easy, light-triggered detachment.
  • To demonstrate the principle of photodetachable adhesion using hydrogel systems.

Main Methods:

  • Fabrication of hydrogels with covalent polymer networks lacking inherent bonding functional groups.
  • In situ formation of a stitching polymer network via an aqueous polymer solution to achieve strong adhesion.
  • Functionalization of the stitching network for UV-light-induced gel-sol transition to enable detachment.

Main Results:

  • Achieved strong adhesion between hydrogels, elastomers, and inorganic solids.
  • Demonstrated tunable adhesion energies, e.g., alginate-polyacrylamide hydrogels showed 1400 J m⁻² before UV and 10 J m⁻² after UV radiation.
  • Confirmed on-demand, easy detachment triggered by UV light exposure.

Conclusions:

  • The developed photodetachable adhesion system successfully combines strong bonding with controlled, light-induced release.
  • This approach offers a versatile platform for applications requiring temporary yet robust material joining.
  • The study elucidates the fundamental physics and chemistry governing this tunable adhesion mechanism.