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[Prevalence of allergy in children with acute rhinosinusitis]
Insights
Allergy is common in children with acute rhinosinusitis (ARS), with over 40% affected by perennial allergens. Allergic rhinitis significantly worsens ARS symptoms and quality of life in pediatric patients.
Area of Science:
- Pediatric Otolaryngology
- Allergy and Immunology
- Respiratory Medicine
Context:
- Acute rhinosinusitis (ARS) is a common pediatric condition.
- The role of allergy in pediatric ARS requires further investigation.
- Understanding allergy prevalence is crucial for effective ARS management in children.
Purpose:
- To determine the prevalence of allergy in children diagnosed with ARS.
- To compare symptom severity and quality of life between allergic and non-allergic pediatric ARS patients.
- To evaluate the impact of specific allergen types (inhalation vs. perennial) on ARS presentation.
Summary:
- A study of 207 children with ARS found that 44.4% had positive skin prick tests to inhalation allergens and 40.6% to perennial allergens, significantly higher than controls.
- Perennial allergies were more prevalent than seasonal allergies in pediatric ARS.
- Allergic ARS patients reported more severe nasal obstruction, discharge, post-nasal drip, and itchy eyes/nose, along with lower quality of life scores (SN-5).
Impact:
- Allergic factors are significant contributors to the development and severity of pediatric ARS.
- Findings highlight the importance of allergy screening in children presenting with ARS.
- This research can inform targeted treatment strategies for pediatric ARS, improving patient outcomes.
Abstract:
Objective:To explore the prevalence of allergy in patients with acute rhinosinusitis (ARS) and evaluate the severity of symptoms in ARS children with or without allergy.Method:Two hundred and seven children (4-12 years of age) with ARS and 85 children of control group were included in our research from June, 2016 to January, 2018. We use questionaire to collect the basic information of pediatric patients. The results of skin prick test (SPT) were recorded. Mothers were required to complete the Sinus and Nasal Quality-of-Life Survey (SN-5).All ARS childern were divided into allergic group and non-allergic group according to the result of SPT. We use binomial distribution to evaluate the population rate. t-test, Chi-square test and Wilcoxon rank-sum test were appropriately used to compare the parameters between two groups.Result:Among the 207 ARS participants in this study, 44.4% participants were shown to response to at least one Inhalation allergen and 40.6% participants were shown to response to at least one perennial allergen. Both ratios were significantly higher than those of the control group. Perennial allergy seems to be much more common than seasonal allergy in pediatric patients with ARS. The most troublesome symptoms among the participants with acute rhinosinusitis combined with allergic rhinitis were nasal obstruction (5.28±1.34), nasal discharge (5.07±1.04), post-nasal drip (4.63±1.31) and itchy eyes/nose (4.28±1.51). Four subscale scores of the SN-5 including nasal obstruction, allergy symptoms, emotional distress and activity limitation in the allergic group were obviously higher than those of the non-allergic group.Conclusion:Allergic factors play an important role in the pathogenesis of pediatric acute rhinosinusitis.
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