Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hearing01:31

Hearing

57.2K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
57.2K
MicroRNAs01:22

MicroRNAs

24.2K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
24.2K
MicroRNAs01:22

MicroRNAs

4.0K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
4.0K
Line Loss01:10

Line Loss

541
The different configurations of source-load connections include wye (star) and delta connections. The relationship between line and phase voltages and currents varies depending on the configuration. When the source is supplying power, it is transmitted through the wires to the load, and during this transmission, some power is absorbed by the wires, leading to line loss.
Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
541
Reducing Line Loss01:18

Reducing Line Loss

389
In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
389
Energy Losses in Transformers01:21

Energy Losses in Transformers

1.3K
In an ideal transformer, it is assumed that there are no energy losses, and, hence, all the power at the primary winding is transferred to the secondary winding. However, in reality,  the transformers always have some energy losses, and, hence, the output power obtained at the secondary winding is less than the input power at the primary winding due to energy losses.
There are four main reasons for energy losses in transformers.
The first cause can be  the high resistance of the...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence of Spin-Interference Effects in Exclusive J/ψ→e^{+}e^{-} Photoproduction in Ultraperipheral Heavy-Ion Collisions.

Physical review letters·2026
Same author

First Observation of Deuteron-Λ Correlations at RHIC.

Physical review letters·2026
Same author

[Dietary serine supplementation inhibits the hepatic macrophage AKT/mTOR pathway and improves primary biliary cholangitis].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2026
Same author

[Dose-response relationship of multidimensional lifestyle with anxiety and depression in children and adolescents: a moderated analysis on overweight/obesity effect].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same author

[Analysis surveillance results of the Neisseria meningitidis carriage rate among healthy population in certain regions of Qinghai Province in 2023].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]·2026
Same author

Observation of Charmonium Sequential Suppression in Heavy-Ion Collisions at the Relativistic Heavy Ion Collider.

Physical review letters·2026

Related Experiment Video

Updated: Feb 1, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
09:44

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

19.8K

[MicroRNA and sensorineural hearing loss].

X L Tang, Y Li, L F Jia

    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
    |December 15, 2018
    PubMed
    Summary

    Sensorineural hearing loss stems from inner ear damage. MicroRNAs are increasingly recognized for their crucial role in regulating gene expression and contributing to the development of this hearing impairment.

    Keywords:
    hearing loss,sensorineuralmicroRNA

    More Related Videos

    Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation
    03:49

    Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

    Published on: October 11, 2024

    1.2K
    Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
    07:13

    Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

    Published on: February 10, 2023

    2.9K

    Related Experiment Videos

    Last Updated: Feb 1, 2026

    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
    09:44

    Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

    Published on: January 25, 2016

    19.8K
    Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation
    03:49

    Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

    Published on: October 11, 2024

    1.2K
    Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
    07:13

    Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

    Published on: February 10, 2023

    2.9K

    Area of Science:

    • Genetics
    • Molecular Biology
    • Otolaryngology

    Context:

    • Sensorineural hearing loss (SNHL) is a prevalent condition affecting the cochlea or auditory pathway.
    • Damage to the inner ear's sensory epithelium is a primary pathological hallmark of SNHL.
    • The causes of SNHL are intricate and varied, necessitating a deeper understanding of underlying molecular mechanisms.

    Purpose:

    • To review the multifaceted role of microRNAs in the pathogenesis of sensorineural hearing loss.
    • To elucidate how microRNAs regulate gene expression relevant to inner ear development and function.
    • To consolidate current research on microRNA involvement in SNHL etiology.

    Summary:

    • MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally.
    • Dysregulation of specific miRNAs has been implicated in the cellular damage characteristic of SNHL.
    • This review synthesizes evidence linking miRNA activity to the development and progression of sensorineural deafness.

    Impact:

    • Highlights the significance of microRNAs as potential diagnostic biomarkers for SNHL.
    • Suggests microRNAs as therapeutic targets for future interventions against hearing loss.
    • Provides a comprehensive overview for researchers investigating the molecular basis of auditory disorders.