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Updated: Feb 1, 2026

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Mimicking and Manipulating Pancreatic Acinar-to-Ductal Metaplasia in 3-dimensional Cell Culture
Published on: February 11, 2019
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[Nasal acinar cell carcinoma:a case report].
Summary
A rare parotid gland tumor, acinar cell carcinoma, can present with unusual nasal symptoms. Surgical resection of this low-grade malignancy led to a good recovery in a 72-year-old patient.
Area of Science:
- Oncology
- Otolaryngology
Background:
- Acinar cell carcinoma is a rare, slow-progressing, low-grade malignant tumor originating from the parotid gland epithelium.
- Diverse tissue types and cell morphology make diagnosis challenging, increasing the risk of missed or incorrect diagnoses.
Observation:
- A 72-year-old patient presented with nasal congestion, bloody sputum, and olfactory loss, without prior surgery or trauma.
- CT and MRI scans indicated soft tissue occupation within the nasal cavity and sinuses.
Findings:
- Endoscopic resection of the nasal cavity and sinus mass was successfully performed under general anesthesia.
- Post-operative follow-up for 1 year showed no recurrence of the tumor.
Implications:
- This case highlights the importance of considering rare parotid gland tumors in the differential diagnosis of sinonasal masses.
- Successful surgical management resulted in complete resolution of nasal symptoms and good patient recovery.
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