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Updated: Jan 31, 2026

Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence
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Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence

Published on: February 21, 2012

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A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression.

Arup Podder1, Seyoung Koo, Jiyeong Lee

  • 1Amrita Centre for Industrial Research & Innovation, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India. b_sankarprasad@cb.amrita.edu.

Chemical Communications (Cambridge, England)
|December 18, 2018
PubMed
Summary

We developed a new rhodamine-based probe (MQR) to visualize cytosolic nicotinamide adenine dinucleotide (NADH) in cells. This sensitive probe can track NADH level changes during metabolic shifts, aiding research into metabolic diseases.

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