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Updated: Jan 31, 2026

In vivo Measurement of Knee Extensor Muscle Function in Mice
Published on: March 4, 2021
Retrieval analysis of a failed synthetic mesh extensor mechanism reconstruction after total knee arthroplasty
Anna Cohen-Rosenblum1, Ashley Volaric2, James A Browne1
1Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.
Abstract:
Extensor mechanism disruption after total knee arthroplasty is a relatively rare but potentially devastating complication. One technique to address this problem involves reconstruction with synthetic mesh. Although there are reports of successful clinical outcomes using this technique, we are not aware of any histological analyses of removed mesh grafts. This case report of a failed mesh reconstruction includes a retrieval analysis demonstrating robust host soft-tissue incorporation into the mesh graft and supports the rationale for continued use of this off-label technique. This case report also highlights the need for careful operative technique when performing these procedures to increase the chance of a successful outcome.
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