[ECMO support in a child with cardiogenic shock due to Kingella Kingae endocarditis]

N Van Sint Jan1, C Valverde2, C Baeza3

  • 1Escuela de Medicina, U. de Chile, Chile.

Insights

This case report details the first instance of Kingella Kingae (KK) endocarditis in a child requiring extracorporeal membrane oxygenation (ECMO) support. The successful use of ECMO highlights its potential in managing severe pediatric infectious endocarditis.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Infective endocarditis (IE) is uncommon in children, particularly without prior cardiac conditions.
  • Kingella Kingae (KK) is a rare causative agent of pediatric IE.
  • Extracorporeal membrane oxygenation (ECMO) provides vital cardiopulmonary support during failure.

Observation:

  • A 19-month-old previously healthy female presented with fever and hand-foot-and-mouth disease, rapidly progressing to refractory cardiogenic shock and multiorgan failure.
  • Veno-arterial ECMO was initiated due to severe hemodynamic compromise.
  • Transthoracic echocardiography revealed mitral valve vegetation, confirming IE caused by KK, with subsequent stroke and two cardiac surgeries.

Findings:

  • This is the first reported case of KK-associated IE necessitating ECMO support.
  • The patient experienced a favorable outcome with ECMO and surgical intervention, being discharged after 73 days.
  • One-year follow-up showed no cardiac sequelae, though mild hemiparesis persisted.

Implications:

  • This case underscores that KK endocarditis, though rare, can lead to severe outcomes including multiorgan failure.
  • ECMO can be a life-saving intervention for pediatric patients with severe IE and cardiogenic shock.
  • Early recognition and aggressive management, including ECMO, are crucial for improving survival in complex pediatric IE cases.
Abstract

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
509
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
500
Shock Waves01:16

Shock Waves

While deriving the Doppler formula for the observed frequency of a sound wave, it is assumed that the speed of sound in the medium is greater than the source's speed through it. When this condition is breached, a shock wave occurs.
When the source's speed approaches the speed of sound, constructive interference between successive wavefronts emitted by the source occurs immediately behind it. Initially, scientists believed that this constructive interference would result in such high...
2.6K
Self-Help Support Groups01:28

Self-Help Support Groups

Self-help support groups are voluntary, community-based organizations that provide a platform for individuals with shared concerns to exchange support, insights, and practical strategies for coping with life challenges. Typically led by group members or paraprofessionals, these groups form a cornerstone of mental health care, especially in reaching populations that are underserved by traditional healthcare systems.
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
352
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
258
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
388