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Updated: Jan 31, 2026

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Fluorescence Lifetime Macro Imager for Biomedical Applications
Published on: April 7, 2023
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Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016
The New England Journal of Medicine
|December 22, 2018
Summary
The global lifetime stroke risk is about 25%, with significant regional variations. This risk increased slightly from 1990 to 2016, highlighting the need for stroke prevention strategies.
Area of Science:
- Epidemiology
- Global Health
- Cardiovascular Disease Research
Background:
- Limited data exists on lifetime stroke risk across diverse populations.
- Estimating lifetime stroke risk is crucial for public health planning and resource allocation.
Purpose of the Study:
- To estimate the global, regional, and country-level lifetime risk of stroke.
- To analyze trends in lifetime stroke risk from 1990 to 2016.
- To compare stroke risks across different socioeconomic and geographic strata.
Main Methods:
- Utilized Global Burden of Disease (GBD) Study 2016 data on stroke incidence and competing mortality risks.
- Calculated cumulative lifetime risks for all stroke types, ischemic stroke, and hemorrhagic stroke.
- Compared lifetime risks between 1990 and 2016, and across sociodemographic index (SDI) quintiles and GBD regions.
Main Results:
- Global lifetime stroke risk was 24.9% in 2016 (men: 24.7%, women: 25.1%).
- Ischemic stroke risk was 18.3%, and hemorrhagic stroke risk was 8.2%.
- Highest risks were observed in high-middle-SDI countries (31.1%), East Asia (38.8%), Central Europe (31.7%), and Eastern Europe (31.6%).
- Global mean lifetime risk increased by 8.9% from 1990 to 2016.
Conclusions:
- In 2016, approximately 25% of adults faced a lifetime risk of stroke.
- Significant geographic disparities in lifetime stroke risk were identified.
- The study underscores the persistent and geographically varied burden of stroke globally.
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