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Feeding practices and growth of infants with Pierre Robin Sequence
Bonnie Dorise1, Amit Trivedi2, Claire Galea3
1Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Sydney, NSW, Australia.
Insights
Infants with Pierre Robin Sequence (PRS) often experience feeding difficulties and malnutrition, leading to longer hospital stays. Early dietitian intervention is crucial for improving growth outcomes in these infants.
Area of Science:
- Pediatric Nutrition
- Neonatal Intensive Care
- Clinical Pediatrics
Background:
- Pierre Robin Sequence (PRS) presents significant feeding challenges in infants.
- Growth and nutritional status are critical during neonatal intensive care unit (NICU) stays.
Purpose of the Study:
- To evaluate the impact of feeding practices on infant growth within the NICU.
- To identify factors influencing feeding difficulties and malnutrition in infants with PRS.
Main Methods:
- Retrospective review of feeding practices in infants with PRS (2006-2017).
- Collected data on demographics, feeding, length of stay (LOS), and malnutrition (weight-for-age Z score < -1).
- Primary outcomes included feeding difficulties, LOS, and malnutrition rates.
Main Results:
- Feeding difficulties were associated with significantly longer LOS (24.1 vs 6.8 days).
- Infants showed a significant decline in Z-scores from birth to discharge (-1.27 vs 0.21).
- Malnutrition affected 26 infants, with intrauterine growth restriction (IUGR) increasing malnutrition likelihood (OR 1.40).
Conclusions:
- Infants with PRS have a high incidence of feeding difficulties and malnutrition.
- Early dietitian intervention is recommended to support growth and energy needs.
- Routine monitoring of growth and feeding is advised for infants with prolonged NICU stays or IUGR.
Objectives:
To assess the impact of feeding practices on growth in infants with Pierre Robin Sequence (PRS) during their inpatient stay in a neonatal intensive care unit in a large tertiary paediatric hospital setting.
Methods:
A retrospective review of feeding practices in infants with PRS was conducted between January 2006 and September 2017. Baseline demographics, nutrition-related and general outcomes were collected. Feeding difficulties, length of stay (LOS) and malnutrition were the primary outcome measures. Feeding difficulties included absence or poor-quality suck, episodes of aspiration, use of proton pump inhibitors or multiple episodes of vomiting. Malnutrition was classified as a weight-for-age Z score of < -1.
Results:
Analysis was conducted on 49 infants with PRS that met eligibility criteria. Feeding difficulties correlated with a longer LOS (24.1 vs 6.8 days (p = 0.001)) Z-scores differed significantly between birth and discharge (0.21(1.84) vs -1.27(2.14)) (p < 0.001*) with malnutrition being evident in 26 infants of which only 17 infants were seen by a dietitian. Presence of intrauterine growth restriction (IUGR) increased the likelihood of malnutrition (OR 1.40(CI-1.11-1.77)).
Conclusion:
Infants with PRS are highly likely to have feeding difficulties and malnutrition. Early intervention by a dietitian is recommended to reduce the impacts of feeding difficulties, meet elevated energy requirements and facilitate growth. Infants with a longer inpatient stay or presence of IUGR should have their growth and feeding routinely monitored.
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