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Published on: July 7, 2023
COMPARATIVE CHARACTERISTIC OF «ALCOHOL DEPRESSION» IN PERSONS WHO PARTICIPATED IN COMBAT OPERATIONS (COMBATANS) AND
O K Napryeyenko1, K M Loganovsky2, N Yu Napryeyenko1
1Bogomolets National Medical University, Taras Shevchenko Boulevard, 13, Kyiv, 01601, Ukraine.
Combatants and Chernobyl survivors with depression and alcohol abuse face significant risks, including suicidal behavior. New diagnostic and treatment approaches are crucial for improving their care and rehabilitation.
Area of Science:
- Psychiatry
- Neuroscience
- Public Health
Background:
- High prevalence of depressive disorders and alcohol abuse among combatants and Chernobyl survivors.
- Need for optimized, comprehensive care based on a biopsychosocial paradigm.
- Existing care gaps for individuals with comorbid depression and alcohol use disorders.
Purpose of the Study:
- To enhance medical care for combatants (Antiterrorist Operation /Joint Forces Operation - ATO/JFO) and Chernobyl Nuclear Power Plant (ChNPP) catastrophe survivors with depression and alcohol abuse.
- To develop and implement new diagnostic, treatment, and prevention principles and algorithms.
- To address the complex interplay of combat stress, radiation exposure, and mental health conditions.
Main Methods:
- Study involved 160 ATO/JFO combatants and 81 Chernobyl liquidators.
- Utilized clinical-anamnestic, socio-demographic, psychopathological, psychodiagnostic, neurophysiological, and neuroimaging methods.
- Included somato-neurological examinations, laboratory tests, and statistical analysis (Student's t-test, chi-squared, Fisher's exact test).
Main Results:
- Depressive syndromes in combatants included depressive-hypochondric (42.5%), asthenic-depressive (20.6%), and anxiety-depressive (19.4%).
- Combatants showed personality changes and altered brain activity; Chernobyl survivors exhibited increased depressive disorders correlated with radiation dose, leading to neurocognitive deficits and secondary alcohol abuse (24%).
- Diverse clinical manifestations of comorbid depression and alcohol dependence necessitate differentiated treatment approaches.
Conclusions:
- Comorbidity of depression and alcohol abuse in combatants and Chernobyl survivors significantly increases suicide risk.
- Proposed diagnostic complex and differentiated interventions can improve medical and social rehabilitation outcomes.
- Integrated biopsychosocial care is essential for this vulnerable population.
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