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Updated: Jan 31, 2026

Enrichment of Bruch's Membrane from Human Donor Eyes
Published on: November 15, 2015
RIDGE-SHAPED MACULA PROGRESSING PARALLEL TO BRUCH MEMBRANE DEFECTS AND MACULAR SUPRACHOROIDAL CAVITATION
Yuxin Fang1, Ran Du1, Jost B Jonas2
1Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan; and.
Purpose:
To report on a progressing ridge-shaped macula parallel to Bruch membrane defects and a macular suprachoroidal cavitation.
Method:
Single case report.
Result:
The right eye of a 54-year-old man with an axial length of 30.96 mm showed 2 extrafoveal Bruch membrane defects with a partial herniation of the retina into the choroidal space and an ophthalmoscopically yellowish area inferior to one of the Bruch membrane defects. Optical coherence tomography revealed a horizontal transfoveal ridge of the sclera, Bruch membrane, and macula and a deepening of the suprachoroidal space, corresponding to the ophthalmoscopically detectable yellowish area and fulfilling the criteria of a macular suprachoroidal cavitation. After a follow-up of 10 years, the height of the ridge increased parallel to a further deepening of the macular suprachoroidal cavitation and an increase in axial length by 0.67 mm.
Conclusion:
The findings support the notion of a progression of a ridge-shaped macula parallel to a further deepening of a macular suprachoroidal cavitation in an axially elongating eye.
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