Related Experiment Video
Updated: Jan 31, 2026

06:34
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
4.7K
Automated, machine learning-based, 3D echocardiographic quantification of left ventricular mass
Valentina Volpato1,2, Victor Mor-Avi1, Akhil Narang1
1Cardiac Imaging Center, University of Chicago Medical Center, Chicago, Illinois.
Echocardiography (Mount Kisco, N.Y.)
|December 29, 2018
Summary
A new machine learning (ML) approach for 3D echocardiography (3DE) automates left ventricular (LV) mass measurement. This ML-based 3DE is accurate, fast, and reproducible, potentially improving clinical use.
Area of Science:
- Cardiovascular Imaging
- Artificial Intelligence in Medicine
- Medical Technology
Background:
- 2D echocardiography has limitations for left ventricular (LV) mass measurement.
- 3D echocardiography (3DE) offers direct LV mass measurements but is time-consuming.
- A novel machine learning (ML) approach automates 3DE analysis for LV mass.
Purpose of the Study:
- To evaluate the accuracy of a new automated ML-based 3DE software for LV mass.
- To compare the ML-3DE approach against cardiac magnetic resonance (CMR) as reference.
- To compare the ML-3DE approach against conventional 3DE volumetric analysis.
Main Methods:
- Prospective study of 23 patients undergoing same-day 3DE and CMR.
- Automated LV mass quantification using ML software (Philips HeartModel) with manual corrections.
- Conventional LV mass analysis using TomTec software and CMR slice-by-slice tracing.
Main Results:
- Automated 3DE LV mass measurements were feasible in 87% of patients.
- ML-3DE results showed good agreement with CMR (bias 5 g, ±37 g) and conventional 3DE (bias 7 g, ±27 g).
- Processing time was significantly reduced (ML-3DE: 1.02 min vs. CMR: 2.20 min, TomTec: 2.36 min).
- High reproducibility was observed for the ML approach (ICC=0.99, CoV=4±5%).
Conclusions:
- The ML-based 3DE algorithm for LV mass is feasible, fast, and accurate.
- This automated approach may facilitate the clinical integration of 3DE for LV mass assessment.
- The study highlights the potential of AI to enhance cardiovascular imaging analysis.
Related Concept Videos
Machines
578
Machines are complex structures consisting of movable, pin-connected multi-force members that work together to transmit forces. One example of a machine is the cutting plier, which is used to cut wires by applying forces to its handles. When equal and opposite forces are exerted on the handles of the cutting plier, they cause the cutting edges to come together and apply equal and opposite reaction forces on the wire, which are greater than the applied forces.
A free-body diagram of the...
A free-body diagram of the...
578
Machines: Problem Solving II
668
Machines are complex structures consisting of movable, pin-connected multi-force members that work together to transmit forces. Consider a lifting tong carrying a 100 kg load. It comprises movable sections DAF and CBG linked together with member AB.
668
Machines: Problem Solving I
714
A toggle clamp is a mechanical device commonly used for holding and clamping objects in various applications, such as woodworking, metalworking, and assembly operations. Consider a toggle clamp subjected to a force of 200 N at the handle. The vertical clamping force can be calculated, provided the dimensions of the toggle clamp are known.
The toggle clamp system is a machine structure consisting of movable, pin-connected multi-force members that form a stabilized system to transmit forces. The...
The toggle clamp system is a machine structure consisting of movable, pin-connected multi-force members that form a stabilized system to transmit forces. The...
714
Avoidance Learning and Learned Helplessness
2.6K
Avoidance learning and learned helplessness are critical concepts in understanding behavioral responses to negative stimuli.
Avoidance learning occurs when an organism learns that a specific behavior can prevent an unpleasant outcome. For example, a student who receives a bad grade may start studying harder to avoid future poor grades. This behavior persists even when the negative outcome is no longer present. Avoidance learning is powerful because it maintains behavior in the absence of the...
Avoidance learning occurs when an organism learns that a specific behavior can prevent an unpleasant outcome. For example, a student who receives a bad grade may start studying harder to avoid future poor grades. This behavior persists even when the negative outcome is no longer present. Avoidance learning is powerful because it maintains behavior in the absence of the...
2.6K
Atomic Mass
70.1K
Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...
70.1K
Molar Mass
86.7K
The identity of a substance is defined not only by the types of atoms or ions it contains but by the quantity of each type of atom or ion. For example, water, H2O, and hydrogen peroxide, H2O2, are alike in that their respective molecules are composed of hydrogen and oxygen atoms. However, because a hydrogen peroxide molecule contains two oxygen atoms, as opposed to the water molecule, which has only one, the two substances exhibit very different properties.
86.7K

