Related Experiment Video
Updated: Jan 31, 2026

Author Spotlight: Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Porphyrin-Hexaphenylbenzene Conjugates via Mixed Cyclotrimerization Reactions
Max M Martin1, Maximilian Dill1, Jens Langer2
1Department Chemie und Pharmazie & Interdisciplinary Center for Molecular Materials (ICMM) , Friedrich-Alexander-Universität Erlangen-Nürnberg , Nikolaus-Fiebiger-Strasse 10 , 91058 Erlangen , Germany.
Abstract:
Mixed cyclotrimerization reactions of diarylacetylenes (tolans) were applied to generate a library of multiple porphyrin-hexaphenylbenzene (HPB) architectures. Successful reactions, which could be influenced by the ratio of tolan starting materials, were conducted using dicobaltoctacarbonyl as a catalyst. Separation of the reaction products was performed by chromatographic and crystallization techniques. The physical properties were investigated with respect to the number of porphyrins per HPB and their substitution pattern.
More Related Videos
11:02Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
Published on: September 14, 2018
10:41Conjugative Mating Assays for Sequence-specific Analysis of Transfer Proteins Involved in Bacterial Conjugation
Published on: January 4, 2017
Related Concept Videos
Phase II Reactions: Miscellaneous Conjugation Reactions
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...
Phase II Conjugation Reactions: Overview
Phase II Reactions: Sulfation and Conjugation with α-Amino Acids
Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
Conjugated Proteins
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Conjugated Proteins