Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Satellite Stem Cells and Muscular Dystrophy

Satellite Stem Cells and Muscular Dystrophy

Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Surviving Severe Obstetric Complications: A Population-Based Analysis of Maternal near Miss.

Medical sciences (Basel, Switzerland)·2026

Same author

Leukocyte Ratios Predict Metastasis, Recurrence, and Mortality in Breast Cancer Patients Receiving Cytotoxic Chemotherapy.

Medical sciences (Basel, Switzerland)·2025

Same author

Gianotti-Crosti Syndrome: A Rare Presentation of the Influenza Virus.

Cureus·2025

Same author

Diffuse Normolipemic Plane Xanthoma Associated With Monoclonal Gammopathy.

Cureus·2025

Same author

Congenital Self-Healing Langerhans Cell Histiocytosis.

Journal of cutaneous medicine and surgery·2025

Same author

Violence at work experienced by nursing professionals working in hospital units: an exploratory and correlational study.

Revista latino-americana de enfermagem·2025

Search research articles

Related Experiment Video

Updated: Jan 31, 2026

A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy

A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy

Published on: December 29, 2017

Hypotrichosis with Juvenile Macular Dystrophy.

Filipa Tavares Almeida¹, Rui Carneiro-Freitas², Regina Caldas¹

¹Department of Dermatovenereology, Hospital de Braga, Braga, Portugal.

International Journal of Trichology

|January 5, 2019

Summary

Hypotrichosis with juvenile macular dystrophy is a rare genetic disorder causing hair loss and vision loss. This case report details a 4-year-old patient diagnosed with this condition, linked to cadherin 3 gene mutations.

Keywords:

Blindness P-cadherin hypotrichosis with juvenile macular dystrophy trichoscopy

More Related Videos

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Published on: January 29, 2020

Author Spotlight: Assessing Intrathecal Gene Therapy Efficacy in Juvenile Rats

Author Spotlight: Assessing Intrathecal Gene Therapy Efficacy in Juvenile Rats

Published on: March 29, 2024

Related Experiment Videos

Last Updated: Jan 31, 2026

A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy

A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy

Published on: December 29, 2017

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Published on: January 29, 2020

Author Spotlight: Assessing Intrathecal Gene Therapy Efficacy in Juvenile Rats

Author Spotlight: Assessing Intrathecal Gene Therapy Efficacy in Juvenile Rats

Published on: March 29, 2024

Area of Science:

Ophthalmology
Genetics
Dermatology

Background:

Hypotrichosis with juvenile macular dystrophy is a rare autosomal recessive genodermatosis.
It presents with hypotrichosis and progressive macular degeneration, potentially causing blindness within the first 30 years of life.

Observation:

A 4-year-old female patient was diagnosed with hypotrichosis with juvenile macular dystrophy.
The diagnosis was based on clinical presentation and genetic analysis.

Findings:

The disease is associated with mutations in the cadherin 3 gene.
These mutations lead to abnormal expression of P-cadherin, a key cell adhesion molecule.

Implications:

Understanding the genetic basis of this disorder is crucial for diagnosis and potential therapeutic strategies.
This case highlights the importance of early diagnosis for managing progressive vision loss.