Related Experiment Video
Updated: Jan 30, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Outcome prediction for Bonebridge candidates based on audiological indication criteria
Wilhelm Wimmer1, Moritz von Werdt2, Georgios Mantokoudis2
1Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland; Department of ENT, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Bone conduction thresholds in the better ear predict outcomes for Bonebridge implants. This suggests refining indication criteria to maximize audiological results for patients with hearing loss.
Area of Science:
- Audiology
- Otorhinolaryngology
- Biomedical Engineering
Background:
- Bonebridge bone conduction implants offer solutions for conductive or mixed hearing loss (CMHL) and single-sided deafness (SSD).
- Current indication criteria for Bonebridge implantation require re-evaluation based on predictive audiological outcomes.
- Preoperative bone conduction thresholds are a key factor in assessing potential implant success.
Purpose of the Study:
- To re-evaluate current indication criteria for Bonebridge implants.
- To estimate audiological outcomes based on preoperative bone conduction thresholds.
- To identify predictors of success for Bonebridge recipients.
Main Methods:
- A cohort of 28 subjects with CMHL or SSD receiving Bonebridge implantation was assessed.
- Linear regression analyzed the influence of preoperative bone conduction thresholds (better/poorer ear), indication group, and language on aided sound field thresholds.
- Logistic regression examined aided word recognition scores in relation to preoperative thresholds, indication group, and language.
Main Results:
- A significant correlation was found between aided sound field thresholds and word recognition with preoperative bone conduction thresholds of the better hearing ear.
- No significant correlation was observed between audiological outcomes and preoperative bone conduction thresholds of the poorer ear, language, or indication group.
- These findings highlight the predictive value of the better ear's bone conduction thresholds.
Conclusions:
- Preoperative bone conduction thresholds of the better hearing ear are crucial for estimating audiological outcomes in Bonebridge recipients.
- Revised indication criteria for Bonebridge implantation should consider maximal bone conduction thresholds of the better ear at 38dB HL.
- These criteria aim to ensure aided sound field thresholds of at least 30dB HL and aided word recognition scores of at least 75%.
Related Concept Videos
Predicting Reaction Outcomes
Indicators
Criteria for Causality: Bradford Hill Criteria - II
Criteria for Causality: Bradford Hill Criteria - I
Cardiovascular Drugs: Classification based on Therapeutic Indications
Predicting Molecular Geometry

