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Reversible Left Ventricular Systolic Dysfunction Secondary to Pazopanib

Kushani Gajjar1, Kathir Balakumaran2, Agnes S Kim2

  • 1Internal Medicine, University of Connecticut Health Center, Farmington, USA.

Cureus
|January 17, 2019
PubMed
Summary

Pazopanib treatment for sarcoma can cause severe heart dysfunction. Stopping the drug led to recovery of the patient's left ventricular ejection fraction, indicating a reversible effect.

Keywords:
cardio-oncologycardiomyopathycardiotoxicityoncologypazopanibtyrosine kinase inhibitorsvascular-endothelial growth factor

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