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Pseudoinflammatory macular dystrophy.

R E Carr, K G Noble

    Transactions of the American Ophthalmological Society
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Pseudoinflammatory macular dystrophy (PMD) is a dominantly inherited condition. Early photocoagulation of subretinal neovascularization is recommended to prevent legal blindness.

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    Area of Science:

    • Ophthalmology
    • Medical Genetics

    Background:

    • Presents a family with pseudoinflammatory macular dystrophy (PMD), a rare inherited retinal disorder.
    • Characterizes PMD as a dominantly inherited condition with onset in the 3rd to 5th decades of life.

    Observation:

    • The earliest sign of PMD is the development of a macular subretinal neovascular network.
    • Visual function tests (ERG, EOG, visual fields, retinal sensitivity) indicate a localized or geographic disease pattern in both early and late stages.

    Findings:

    • PMD requires differentiation from other hereditary conditions causing subretinal neovascularization, such as angioid streaks, vitelliform dystrophy, dominant drusen, optic nerve drusen, and myopia.
    • Untreated PMD invariably leads to legal blindness.

    Implications:

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    • Early detection and intervention are crucial for managing PMD.
    • Intense photocoagulation targeting subretinal neovascularization is suggested as a potential treatment to preserve visual function and prevent blindness.