Diagnosis and management of the primary hydatidiform mole

Hydatidiform mole may be categorized as either complete or partial on the basis of gross morphology, histology, and karyotype. The diagnosis, natural history, and management of patients with complete and partial moles are reviewed in detail. The controversy concerning chemoprophylaxis at the time of molar evacuation is also discussed. Furthermore, subsequent reproductive outcome in patients with both complete and partial moles is analyzed.