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Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
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Salvia mellifera-How Does It Alleviate Chronic Pain?
James David Adams1, Steven Guhr2, Enrique Villaseñor3
1Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90089, USA. jadams@usc.edu.
Medicines (Basel, Switzerland)
|January 26, 2019
Summary
Black sage sun tea offers a novel foot soak treatment for chronic pain. Its compounds may interrupt the pain chemokine cycle, providing long-term relief for patients.
Area of Science:
- Ethnobotany
- Pharmacology
- Pain Management
Background:
- Black sage (Salvia mellifera) is a plant with traditional medicinal uses.
- Chronic pain affects millions globally, with limited effective long-term treatments.
- The pain chemokine cycle is a proposed mechanism underlying chronic pain states.
Observation:
- A sun tea preparation from black sage was utilized as a foot soak.
- Patients with chronic pain received this topical treatment.
- Reported outcomes included improvements in pain levels.
Findings:
- Monoterpenoids and diterpenoids present in black sage tea were identified as key components.
- These compounds demonstrated potential to penetrate the skin of the feet.
- The preparation may inhibit the pain chemokine cycle, a potential driver of chronic pain.
Implications:
- Topical application of black sage preparation shows promise for managing chronic pain.
- This natural remedy could offer a new therapeutic avenue for pain management.
- Further research into the phytochemistry and mechanism of action is warranted.
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