Contrast-Enhanced Colosonography for the Evaluation of Children With an Imperforate Anus

Jeanne S Chow1, Harriet J Paltiel1, Horacio M Padua1

  • 1Department of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.

Insights

Contrast-enhanced colosonography (ceCS) offers a radiation-free method to visualize anorectal malformations in children. This novel ultrasound technique accurately depicts complex anatomy, improving preoperative planning and patient safety.

Area of Science:

  • Pediatric Surgery
  • Diagnostic Imaging
  • Medical Ultrasound

Background:

  • Anorectal malformations (ARMs) require precise preoperative anatomical assessment for surgical planning.
  • Traditional imaging methods like fluoroscopy involve ionizing radiation, posing risks to pediatric patients.

Purpose of the Study:

  • To introduce and evaluate a novel contrast-enhanced ultrasound technique for preoperative imaging of pediatric anorectal malformations.
  • To compare the efficacy of contrast-enhanced colosonography (ceCS) with traditional fluoroscopic methods.

Main Methods:

  • A case series involving six pediatric patients with ARM (without perineal fistula) was conducted.
  • Patients underwent both fluoroscopic distal colostography and the novel contrast-enhanced colosonography (ceCS).
  • Surgical findings were used to confirm the accuracy of both imaging modalities.

Main Results:

  • Contrast-enhanced colosonography (ceCS) precisely demonstrated complex anatomical relationships in all evaluated cases.
  • The results from ceCS correlated well with surgical confirmations.
  • ceCS provided detailed anatomical visualization without the use of ionizing radiation.

Conclusions:

  • Contrast-enhanced colosonography (ceCS) is a safe and effective method for preoperative anatomical assessment in pediatric patients with anorectal malformations.
  • ceCS offers a significant advantage over fluoroscopic studies due to the absence of ionizing radiation, enhancing patient safety.

Related Concept Videos

Self-Evaluation: Self-Enhancement and Self-Verification03:00

Self-Evaluation: Self-Enhancement and Self-Verification

Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
5.8K
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
1.2K
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
13.4K
Bioavailability Enhancement: Drug Solubility Enhancement01:16

Bioavailability Enhancement: Drug Solubility Enhancement

Body:Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...
255
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
292
Bioavailability Enhancement: Drug Permeability Enhancement01:27

Bioavailability Enhancement: Drug Permeability Enhancement

Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...
203