Unusual fungal infections associated with immunologic hyporeactivity

Two patients had unusual fungal infections, considered to be contaminants, which suggested immunologic hyporeactivity. One patient with a Fusarium infection had an associated occult malignancy. The other patient had an initial localized, then disseminated Curvularia infection. Both patients, following analysis of subpopulations of lymphocytes, showed evidence of relative T and B cell defects.