COMPARATIVE ANALYSIS OF WHOLE CARTILAGE TISSUE THERMOSTABILITY IN DISEASED PATIENTS VERSUS INJURED PATIENTS

We conducted comparative thermodynamic analysis of femoral cartilages tissue of injured (healthy) patients and patients with congenital hip dislocation. It is shown, that temperature which corresponds to maximum of heat absorption peak of femoral cartilages tissue of diseased patient is on 6.4oC lower than heat absorption peak of femoral cartilages tissue of healthy patient. Heat absorbed during denaturation process in all these cases are close to each other with experimental error accuracy and corresponds to 52±2.6, 51±2.6 and 50±2.5 J/g of dried biomass accordingly. Analysis of the published data makes it possible to assert that the dominant heat absorption stage on DSC curves of tested fresh tissues samples is associated with melting of collagen fibers, hence the thermal stability of the collagen fibers in the patient's tissue is reduced relative to norm.