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Updated: Jan 30, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Cerebrovascular Disease: Primary and Secondary Stroke Prevention
Fan Z Caprio1, Farzaneh A Sorond1
1Division of Stroke and Neurocritical Care, Northwestern University Feinberg School of Medicine, 625 North Michigan Avenvue, Suite 1150, Chicago, IL 60611, USA.
Abstract:
Despite advances in earlier diagnosis and available aggressive treatments for vascular risk factors, stroke remains a leading cause of death and long-term disability worldwide. Disparities exist in stroke risk, rates of stroke, and treatment. Stroke is a heterogeneous disease with multiple additive risk factors and causes. Primary prevention of stroke focusing on risk factor modification plays an important role in reducing the burden of stroke in an aging population. Secondary prevention of recurrent strokes relies on the workup and a tailored treatment targeted at the mechanisms responsible for the incident stroke or transient ischemic attack.
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