Temperature sensitive polymer-dispersive liquid-liquid microextraction with gas chromatography-mass spectrometry for...

A novel dispersive liquid-liquid microextraction method based on temperature-sensitive polymer-induced phase separation was assessed for the determination of phenol, 2,4-dichlorophenol (2,4-DCP), β-naphthol, and bisphenol A. The interaction between β-cyclodextrin-poly (N-isopropylacrylamide) and 2,4-DCP was investigated. The results showed that there was an interaction between 2,4-DCP and the polymer with coiled structures and globular structures. The parameters that affected the extraction of phenols were optimized for the peak area. Under optimal conditions, the correlation coefficients were in the range of 0.9828-0.9990. The limits of detection for all the analytes varied from 0.01 to 1.0 μg L^-1, and the limits of quantification were between 0.04 and 3.50 μg L^-1. The established method was applied successfully to analyze three moat river samples. The relative recoveries were between 81.3 and 117.3%, and the relative standard deviations were less than 17%.