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Updated: Jan 30, 2026

Isolation and Transplantation of Hematopoietic Stem Cells HSCs
Published on: February 25, 2007
Biomarkers for Early Complications After Hematopoietic Stem Cell Transplantation
Courtney M Rowan1, Sophie Paczesny2
1Department of Pediatrics, Division of Critical Care, Indiana University School of Medicine, 705 Riley Hospital Drive, Room 4900, Indianapolis, IN 46202, USA.
Abstract:
Advances in the field of omics have led to a significant expansion in biomarkers identified for complications after hematopoietic stem cell transplantation (HSCT). Biomarkers can offer an effective method for early identification of a specific disease and can be used to guide therapies. Ongoing investigations to discover biomarkers for acute graft-versus-host disease as well as other post-HSCT complications may improve early diagnosis, prognosis, and the development of new therapeutic targets. The authors review the most recent and validated diagnostic, prognostic, predictive, and response to treatment biomarkers for early complications following HSCT consistent with 2014 NIH consensus on biomarker criteria.
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