Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.4K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.4K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

993
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
993
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
Visual System01:26

Visual System

1.8K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
1.8K
Visual Agnosia01:12

Visual Agnosia

1.1K
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
1.1K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

9.2K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
9.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine Learning With Optical Coherence Tomography for Glaucoma Diagnosis.

Journal of glaucoma·2026
Same author

Association between 24-Hour Blood Pressure and Rates of Retinal Nerve Fiber Layer Progression in Glaucoma: The Vascular Imaging in Glaucoma Study.

American journal of ophthalmology·2026
Same author

Detecting glaucoma progression through optic nerve head hemoglobin concentration using automated colorimetric analysis.

European journal of ophthalmology·2026
Same author

Convolutional Graph Isomorphism Network to Detect Glaucomatous Visual Field Defects.

Ophthalmology science·2026
Same author

Influence of Intraocular Pressure on Clinical Decision-Making in Glaucoma Management.

JAMA ophthalmology·2026
Same author

Performance of a Small Language Model Versus a Large Language Model in Answering Glaucoma Frequently Asked Patient Questions: Development and Usability Study.

JMIR AI·2026
Same journal

Dual-Hit Myopia Mechanism Unveiled by Multi-Omics: Opn1mw Deficiency Primed the Retina for Exaggerated Response to Environmental Defocus.

Investigative ophthalmology & visual science·2026
Same journal

Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.

Investigative ophthalmology & visual science·2026
Same journal

The Molecular Basis of Ocular Aging: Mechanisms, Pathologies, and Emerging Therapeutics.

Investigative ophthalmology & visual science·2026
Same journal

Sensory Eye Dominance Remains Stable Across Binocular Combination and Rivalry in Normal and Anisometropic Amblyopic Vision.

Investigative ophthalmology & visual science·2026
Same journal

Exosome-Associated Gene Network and the Role of SPP1 in Herpes Stromal Keratitis and the Therapeutic Modulation by Ursolic Acid.

Investigative ophthalmology & visual science·2026
Same journal

Nonlinear Associations of Estimated Glucose Disposal Rate With Incident Age-Related Eye Diseases: Implications for Metabolic Risk Stratification.

Investigative ophthalmology & visual science·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K

Visual Crowding in Glaucoma.

Nara G Ogata1, Erwin R Boer2, Fábio B Daga1

  • 1Duke Eye Center, Department of Ophthalmology, Duke University, Durham, North Carolina, United States.

Investigative Ophthalmology & Visual Science
|February 5, 2019
PubMed
Summary
This summary is machine-generated.

Glaucoma patients experience increased visual crowding, impacting daily tasks. This effect correlates with neural loss measured by optical coherence tomography (OCT), not standard visual field tests.

More Related Videos

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
08:20

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

Published on: May 1, 2020

7.2K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K

Related Experiment Videos

Last Updated: Jan 29, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K
In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
08:20

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding

Published on: May 1, 2020

7.2K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Perception

Background:

  • Visual crowding is a phenomenon where object recognition is impaired in clutter, limiting peripheral vision.
  • Glaucoma damages peripheral vision, suggesting it may exacerbate visual crowding effects.

Purpose of the Study:

  • To investigate if glaucoma-induced neural loss intensifies visual crowding.
  • To correlate visual crowding severity with glaucoma's impact on visual field sensitivity and retinal nerve fiber layer thickness.

Main Methods:

  • Assessed critical spacing (scritical) for letter orientation discrimination in glaucoma patients and controls.
  • Correlated scritical values with standard automated perimetry (SAP) mean sensitivity (MS) and optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness.

Main Results:

  • Glaucoma patients exhibited significantly worse scritical values compared to healthy controls (P = 0.007).
  • scritical measurements strongly correlated with RNFL thickness (R2 = 26%; P < 0.001).
  • No significant association was found between scritical and SAP MS (P = 0.947).

Conclusions:

  • Glaucoma leads to pronounced visual crowding, even with mild visual field loss.
  • The degree of neural loss, quantified by OCT, is linked to the severity of visual crowding.
  • Findings suggest visual crowding significantly impacts daily functioning for glaucoma patients.