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Hyponatremia Presenting with Recurrent Mania.
Sahil Parag1, Eduardo D Espiridion2
1Medical Education and Simulation, West Virginia School of Osteopathic Medicine, Lewisburg, USA.
Cureus
|February 7, 2019
Summary
Primary psychogenic polydipsia (PPD) can cause recurrent mania in bipolar disorder patients. This case highlights the challenge of diagnosing and managing hyponatremia-induced manic symptoms in bipolar disorder patients with PPD.
Area of Science:
- Neuroscience
- Psychiatry
- Endocrinology
Background:
- Primary psychogenic polydipsia (PPD) is a rare condition affecting thirst regulation, often linked to psychiatric disorders.
- While PPD is documented in schizophrenia, its association with bipolar disorder is seldom reported.
Observation:
- A patient with bipolar disorder type 1 repeatedly presented with hyponatremia and manic symptoms.
- These manic episodes, characterized by mood lability and psychomotor agitation, recurred despite medication adjustments and oral sodium chloride treatment.
Findings:
- The study posits that the patient's manic symptoms were a direct result of chronic hyponatremia caused by PPD.
- This case demonstrates the diagnostic and therapeutic challenges in managing bipolar disorder patients with PPD-induced hyponatremia.
Implications:
- This case underscores the importance of considering PPD in recurrent hyponatremia and unexplained mood disturbances, particularly in bipolar disorder patients.
- Further case studies are crucial for understanding effective management and treatment strategies for this complex interplay between PPD and bipolar disorder.
