Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrical Current01:10

Electrical Current

7.1K
Electrical current is defined as the rate at which charge flows. When there is a large current present, such as that used to run a refrigerator, a large amount of charge moves through the wire in a small amount of time. If the current is small, such as that used to operate a handheld calculator, a small amount of charge moves through the circuit over a long period of time. The SI unit for current is the ampere (A), named for the French physicist André-Marie Ampère (1775–1836).
7.1K
Whole Body Regeneration01:33

Whole Body Regeneration

4.1K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.1K
Liver Regeneration01:24

Liver Regeneration

4.3K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
4.3K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

5.1K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
5.1K
Current Density01:21

Current Density

5.1K
The total amount of current flowing through one unit value of a cross-sectional area is referred to as current density. If the current flow is uniform, the amount of current flowing through a conductor is the same at all points along the conductor, even if the conductor area varies. The current density consists of the local magnitude and direction of the charge flow, which varies from point to point. Current density is measured in amperes per meter square, and direction is defined as the net...
5.1K
Eddy Currents01:25

Eddy Currents

2.6K
Since eddy currents occur only in conductors, magnets can separate metals from other materials. For example, in a recycling center, trash is dumped in batches down a ramp, beneath which lies a powerful magnet. Conductors in the trash are slowed by eddy currents, while nonmetals in the trash move on, separating from the metals. This works for all metals, not just ferromagnetic ones.
Other major applications of eddy currents appear in metal detectors and the braking systems of trains and roller...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biocompatibility With Osteogenic Potential of Premixed Bioceramic Cements for Use in Apical Surgery.

Australian endodontic journal : the journal of the Australian Society of Endodontology Inc·2026
Same author

A ferroelectric-ionic-trapping transistor for low power and secure neuromorphic computing.

Nature communications·2026
Same author

A novel observation of negative differential resistance in a standard CMOS transistor and its application to a compact frequency doubler.

Microsystems & nanoengineering·2026
Same author

Impact of dose-adjusted tacrolimus exposure phenotype on outcomes in kidney transplantation: a large-scale multicenter cohort study.

Frontiers in immunology·2026
Same author

Effect of polyphosphates on productivity and physiological characteristics in laying hens.

Journal of animal science and technology·2026
Same author

A preoperative nomogram and web-based clinical decision support system for predicting early renal function after living donor kidney transplantation: a retrospective multicenter cohort study.

International journal of surgery (London, England)·2025
Same journal

Engineering next-generation organoids: A review on bioprinting strategies, bioink innovations, and frontier applications.

Journal of tissue engineering·2026
Same journal

Mechanical regulation of mesenchymal stem cell osteogenesis, bone matrix homoeostasis, and skeletal pathology.

Journal of tissue engineering·2026
Same journal

Chondrocyte metabolic transition from proliferation to quiescence revealed by FLIM in postnatal mouse knee joints.

Journal of tissue engineering·2026
Same journal

Cell-free therapy for alopecia via the secretome of hiPSC-derived dermal papilla cells.

Journal of tissue engineering·2026
Same journal

Cold-stimulated browning graft fat enhances burn wound recovery through accelerating DAMP-ADSC activation.

Journal of tissue engineering·2026
Same journal

Genetically modified bone marrow cells halt mitral cell loss by modulating inflammation and protecting against DNA damage.

Journal of tissue engineering·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

11.9K

Pulp-dentin regeneration: current approaches and challenges.

Chanyong Jung1,2, Sangwan Kim2, Taeuk Sun2

  • 1Department of Dentistry, Aerospace Medical Center, Cheongju, Korea.

Journal of Tissue Engineering
|February 8, 2019
PubMed
Summary
This summary is machine-generated.

Regenerative endodontics offers advantages for immature teeth with apical periodontitis, but current revascularization methods face clinical challenges. This review addresses these drawbacks and guides future research toward successful clinical translation.

Keywords:
Regenerative endodonticspulp regenerationrevascularizationtissue engineering

More Related Videos

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.3K
Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
05:16

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models

Published on: October 27, 2023

1.8K

Related Experiment Videos

Last Updated: Jan 29, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

11.9K
Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.3K
Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models
05:16

Author Spotlight: Enhancing Dental Pulp Research with Improved Mouse Models

Published on: October 27, 2023

1.8K

Area of Science:

  • Dentistry
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Regenerative endodontic procedures (REPs) offer biological and clinical benefits for immature permanent teeth with apical periodontitis.
  • REPs represent a paradigm shift towards regenerating pulp-dentin tissues, moving beyond traditional restorative materials.
  • Significant research has focused on stem/progenitor cells, scaffolds, and biomolecules for pulp tissue engineering.

Purpose of the Study:

  • To review the challenges and drawbacks encountered in current clinical regenerative endodontic procedures.
  • To summarize recent research findings in pulp tissue engineering and regenerative endodontics.
  • To provide direction for transitioning basic research findings into successful clinical practice.

Main Methods:

  • Literature review of preclinical and clinical studies on regenerative endodontics.
  • Analysis of current clinical approaches to pulp revascularization.
  • Synthesis of research on stem cells, scaffolds, and biomolecules for pulp regeneration.

Main Results:

  • Current revascularization techniques in regenerative endodontics present several clinical drawbacks leading to unfavorable outcomes.
  • Despite advancements in stem cell therapies and biomaterials, clinical translation remains challenging.
  • A gap exists between basic science research and predictable clinical application of regenerative endodontic techniques.

Conclusions:

  • Addressing the identified clinical challenges is crucial for improving the success rates of regenerative endodontics.
  • Further research integrating stem cells, biomaterials, and growth factors is needed.
  • Bridging the gap between bench research and clinical practice is essential for advancing regenerative endodontic therapy.